Immanuel Arasar Ayurveda Medical College is located in Edavilagam, Nattalam, Marthandam, Kanyakumari (Dist). Marthandam is the largest town in the district. It derived its name from the Founder and ruler of Travancore, Anizham Thirunal Marthanda Varma. Marthandam is famous for honey, cashew nut processing, rubber, and hand-embroidered motifs. The area is full of greenery, and there is a river adjoining. It is also a major trade centre due to its location bordering Kerala. It is one of the most fertile lands of Tamil Nadu.

Kanyakumari district has a varied topography with the sea on three sides and the mountains of the Western Ghats bordering the northern side. Except for a small stretch of land to the west of Kanyakumari town, almost the entire district is sandwiched between the Western Ghats and the Arabian Sea – the only district in Tamilnadu state facing the Arabian Sea.

The Institute is situated about 4 kilometers from the Railway Station and about 47 kilometers from Trivandrum International Airport. National Highways, No. 66 from kanyakumari to Bombay pass, through Nattalam, Marthandam.